The N-terminal amine is one of the three nitrogen donors to copper. Glycine has no side chain, so nothing competes with that coordination or crowds the metal. Its position at the N-terminus is what makes the amine available.
Replacing it with a bulkier residue would change the geometry of the site.
The imidazole ring is a classic copper ligand and the anchor of the complex. Together with the glycine amine and the deprotonated backbone amide between them, it completes a stable chelate around copper(II). Histidine is also the residue most sensitive to pH in this role, because the imidazole protonates at lower pH and loses the metal.
It is the residue that makes GHK a copper-binding peptide rather than just a tripeptide.
The lysine side chain does not coordinate copper in the complex; it remains protonated and positively charged at physiological pH. That charge keeps the complex soluble and gives the molecule its net positive character. It is also the residue that pairs with trifluoroacetate after synthesis.
GHK-Cu is supplied by REVIVE LAB UAE for laboratory research use only, with identity by mass spectrometry and purity by HPLC for the batch. It is not for human or veterinary use, and no dosing, administration or protocol guidance is provided.
| Format | Strength | Price | Availability |
|---|---|---|---|
| GHK-Cu Pack | 50 mg | AED 425 | In stock |
Delivery is AED 40 flat and free on orders over AED 700. Payment is cash on delivery anywhere in the UAE, or USDT (TRC20) in advance, which takes 5% off the order total.
The N-terminal amine is one of the three nitrogen donors to copper. Glycine has no side chain, so nothing competes with that coordination or crowds the metal. Its position at the N-terminus is what makes the amine available.
No. REVIVE LAB UAE supplies research materials and provides no dosing, administration or protocol guidance of any kind. Every product is sold for laboratory research use only and is not for human or veterinary consumption.
Stock is held in Dubai. An order confirmed before 4 PM Dubai time is dispatched the same working day, reaching Dubai and Abu Dhabi the same day and the remaining emirates within 24 hours. Delivery is AED 40 flat and free over AED 700.
Supplied for laboratory research use only. Not for human or veterinary consumption. REVIVE LAB UAE provides no dosing, administration or protocol guidance.