In adults the long bones cannot lengthen, so excess hormone thickens bone and soft tissue instead: the acral enlargement that named the condition. It also raises IGF-1, causes insulin resistance, enlarges organs and increases cardiovascular and joint disease. In children the same excess produces gigantism. The condition is treated by removing the tumour or by blocking the hormone with a somatostatin analogue or the receptor antagonist pegvisomant.
Acromegaly is the clearest evidence that the hormone has effects beyond growth throughout adult life.
Children without the hormone grow slowly and reach a short adult height; this was the condition Raben treated in 1958. Adults with deficiency, often after pituitary surgery, show reduced lean mass, increased fat, low bone density and reduced exercise capacity. Laron syndrome, with a defective receptor, shows the same picture despite high hormone levels and is the human proof that the receptor and IGF-1 are necessary.
Individuals with Laron syndrome have been reported to have very low rates of cancer and diabetes, an observation that has driven research into the axis and ageing.
The hormone is necessary for normal growth and has lifelong metabolic actions; both deficit and excess are harmful; and the receptor and IGF-1 lie on the path. This is physiology, not a description of any use of the material.
Somatropin is supplied by REVIVE LAB UAE for laboratory research use only, with identity and purity documented for the batch. It is not for human or veterinary use, and no dosing, administration or protocol guidance is provided.
| Format | Strength | Price | Availability |
|---|---|---|---|
| HGH Somatropin Pack | 24 mg (72 IU) | AED 850 | In stock |
Delivery is AED 40 flat and free on orders over AED 700. Payment is cash on delivery anywhere in the UAE, or USDT (TRC20) in advance, which takes 5% off the order total.
In adults the long bones cannot lengthen, so excess hormone thickens bone and soft tissue instead: the acral enlargement that named the condition. It also raises IGF-1, causes insulin resistance, enlarges organs and increases cardiovascular and joint disease. In children the same excess produces gigantism. The condition is treated by removing the tumour or by blocking the hormone with a somatostatin analogue or the receptor antagonist pegvisomant.
No. REVIVE LAB UAE supplies research materials and provides no dosing, administration or protocol guidance of any kind. Every product is sold for laboratory research use only and is not for human or veterinary consumption.
Stock is held in Dubai. An order confirmed before 4 PM Dubai time is dispatched the same working day, reaching Dubai and Abu Dhabi the same day and the remaining emirates within 24 hours. Delivery is AED 40 flat and free over AED 700.
Supplied for laboratory research use only. Not for human or veterinary consumption. REVIVE LAB UAE provides no dosing, administration or protocol guidance.