How somatropin appears in a mass spectrometer, compared with a peptide

Published 24 October 2026 · REVIVE LAB UAE Research Desk · 5 min read
The average molecular mass of 22 kDa somatropin is about 22,124 daltons. In electrospray ionisation a protein this size carries many charges, appearing as an envelope of peaks that must be deconvoluted to a neutral mass. The result confirms the intact sequence and disulfide state within the resolution of the instrument; it does not by itself resolve deamidation or a single oxidation, which require higher resolution or peptide mapping.

The charge envelope

A protein with dozens of basic residues picks up ten to twenty or more protons in electrospray, so the spectrum shows a series of peaks at successively lower mass-to-charge values. Software reads the spacing and reconstructs the neutral mass. A tripeptide gives one peak; somatropin gives a comb.

Average mass is quoted for proteins this size because the isotope peaks merge into one unresolved envelope on most instruments.

What the intact mass confirms

That the full 191-residue chain is present with both disulfides formed — reduction adds two daltons per bond. Truncations, an extra methionine from expression, or a missed signal-peptide cleavage all shift the mass detectably. It is the first identity check for a recombinant protein.

A difference of one dalton, as in deamidation, is within the envelope width on a standard instrument.

What it does not resolve

Single-site modifications, the position of any modification, and the disulfide pairing. Those come from peptide mapping, where the protein is digested and each fragment measured individually.

Somatropin is supplied by REVIVE LAB UAE for laboratory research use only, with identity and purity documented for the batch. It is not for human or veterinary use, and no dosing, administration or protocol guidance is provided.

What it costs

FormatStrengthPriceAvailability
HGH Somatropin Pack24 mg (72 IU)AED 850In stock

Delivery is AED 40 flat and free on orders over AED 700. Payment is cash on delivery anywhere in the UAE, or USDT (TRC20) in advance, which takes 5% off the order total.

Frequently asked

The charge envelope?

A protein with dozens of basic residues picks up ten to twenty or more protons in electrospray, so the spectrum shows a series of peaks at successively lower mass-to-charge values. Software reads the spacing and reconstructs the neutral mass. A tripeptide gives one peak; somatropin gives a comb.

Does REVIVE LAB UAE provide dosing guidance?

No. REVIVE LAB UAE supplies research materials and provides no dosing, administration or protocol guidance of any kind. Every product is sold for laboratory research use only and is not for human or veterinary consumption.

How fast is delivery in the UAE?

Stock is held in Dubai. An order confirmed before 4 PM Dubai time is dispatched the same working day, reaching Dubai and Abu Dhabi the same day and the remaining emirates within 24 hours. Delivery is AED 40 flat and free over AED 700.

HGH Somatropin Pack — in stock, dispatched from Dubai
HPLC-verified, lot certificate on every carton, 24-hour delivery nationwide. Browse the catalogue → All peptides UAE

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Supplied for laboratory research use only. Not for human or veterinary consumption. REVIVE LAB UAE provides no dosing, administration or protocol guidance.