The coding sequence was built from a chemically synthesised fragment for the first 24 codons joined to complementary DNA for the rest, placed under a bacterial promoter, and expressed. The product accumulated inside the cells and was recovered and characterised as growth hormone by immunological and biological assays.
The extra methionine came from the bacterial start codon, which E. coli does not remove from this protein.
Until then every milligram of human growth hormone came from human pituitaries collected post mortem, a supply that was scarce and, as became clear in 1985, carried a transmissible disease risk. A fermentation source removed both constraints. The method generalised to other proteins and is the basis of the biologics industry.
Protropin, the methionyl product, was approved in the United States in 1985.
Later processes secreted the protein into the bacterial periplasm, where the signal peptide is cleaved and the natural 191-residue sequence is recovered without the methionine. That natural-sequence product is somatropin; the 192-residue form is somatrem.
Somatropin is supplied by REVIVE LAB UAE for laboratory research use only, with identity and purity documented for the batch. It is not for human or veterinary use, and no dosing, administration or protocol guidance is provided.
| Format | Strength | Price | Availability |
|---|---|---|---|
| HGH Somatropin Pack | 24 mg (72 IU) | AED 850 | In stock |
Delivery is AED 40 flat and free on orders over AED 700. Payment is cash on delivery anywhere in the UAE, or USDT (TRC20) in advance, which takes 5% off the order total.
The coding sequence was built from a chemically synthesised fragment for the first 24 codons joined to complementary DNA for the rest, placed under a bacterial promoter, and expressed. The product accumulated inside the cells and was recovered and characterised as growth hormone by immunological and biological assays.
No. REVIVE LAB UAE supplies research materials and provides no dosing, administration or protocol guidance of any kind. Every product is sold for laboratory research use only and is not for human or veterinary consumption.
Stock is held in Dubai. An order confirmed before 4 PM Dubai time is dispatched the same working day, reaching Dubai and Abu Dhabi the same day and the remaining emirates within 24 hours. Delivery is AED 40 flat and free over AED 700.
Supplied for laboratory research use only. Not for human or veterinary consumption. REVIVE LAB UAE provides no dosing, administration or protocol guidance.