Cys53 to Cys165 spans more than a hundred residues and closes a large loop that constrains the relative position of the helices. Breaking it changes the fold significantly. It is the structurally important bond.
It forms in the oxidising environment the protein is secreted into, and in recombinant production it must form correctly during folding or refolding.
Cys182 to Cys189 closes a seven-residue loop near the carboxyl terminus. It has a smaller structural role and is near the receptor-binding surface. Both bonds are present in all native isoforms.
Together they give somatropin its two intrachain bridges; there are no free cysteines in the native protein.
The protein is digested under non-reducing conditions and the fragments analysed by mass spectrometry; peptides still joined by a disulfide appear at the combined mass, and their identities fix which cysteines are paired. This is a standard identity test for disulfide-containing biologics and is one of the ways a recombinant protein certificate differs from a peptide certificate.
Somatropin is supplied by REVIVE LAB UAE for laboratory research use only, with identity and purity documented for the batch. It is not for human or veterinary use, and no dosing, administration or protocol guidance is provided.
| Format | Strength | Price | Availability |
|---|---|---|---|
| HGH Somatropin Pack | 24 mg (72 IU) | AED 850 | In stock |
Delivery is AED 40 flat and free on orders over AED 700. Payment is cash on delivery anywhere in the UAE, or USDT (TRC20) in advance, which takes 5% off the order total.
Cys53 to Cys165 spans more than a hundred residues and closes a large loop that constrains the relative position of the helices. Breaking it changes the fold significantly. It is the structurally important bond.
No. REVIVE LAB UAE supplies research materials and provides no dosing, administration or protocol guidance of any kind. Every product is sold for laboratory research use only and is not for human or veterinary consumption.
Stock is held in Dubai. An order confirmed before 4 PM Dubai time is dispatched the same working day, reaching Dubai and Abu Dhabi the same day and the remaining emirates within 24 hours. Delivery is AED 40 flat and free over AED 700.
Supplied for laboratory research use only. Not for human or veterinary consumption. REVIVE LAB UAE provides no dosing, administration or protocol guidance.