The two receptors share substantial structural similarity and overlapping downstream machinery. Hybrid receptors containing one half of each are also described, and their ligand behaviour is not simply the average of the two.
That relatedness is a biological fact rather than an inconvenience, but it does set a limit on how cleanly a result can be assigned.
IGF-1 prefers its own receptor and insulin prefers the insulin receptor, and at sufficient concentration each can engage the other. "Selective" in most of this literature means relatively, within a concentration range, in a particular system.
So an effect observed at high concentration carries less attribution weight than the same effect at low concentration, and a write-up that omits the concentration has dropped the part that mattered.
Receptor-level attribution in this literature rests on more than a ligand: blocking antibodies, receptor knockdown, or comparison across cells differing in receptor complement. In their absence a result identifies the ligand and the system, not the receptor engaged.
IGF-1 LR3 is supplied as a research material for exactly this kind of work, with no dosing or protocol guidance of any kind.
| Format | Strength | Price | Availability |
|---|---|---|---|
| IGF-1 LR3 Pack | 1 mg | AED 650 | In stock |
Delivery is AED 40 flat and free on orders over AED 700. Payment is cash on delivery anywhere in the UAE, or USDT (TRC20) in advance, which takes 5% off the order total.
The two receptors share substantial structural similarity and overlapping downstream machinery. Hybrid receptors containing one half of each are also described, and their ligand behaviour is not simply the average of the two.
No. REVIVE LAB UAE supplies research materials and provides no dosing, administration or protocol guidance of any kind. Every product is sold for laboratory research use only and is not for human or veterinary consumption.
Stock is held in Dubai. An order confirmed before 4 PM Dubai time is dispatched the same working day, reaching Dubai and Abu Dhabi the same day and the remaining emirates within 24 hours. Delivery is AED 40 flat and free over AED 700.
Supplied for laboratory research use only. Not for human or veterinary consumption. REVIVE LAB UAE provides no dosing, administration or protocol guidance.