Blood was drawn years before diagnosis and IGF-1 measured later in stored samples, so the association is prospective and not caused by the tumour. Many studies since have confirmed modest associations for prostate, breast and colorectal cancer, with relative risks in later meta-analyses lower than the first reports. IGFBP-3 was examined alongside and its role is less consistent.
An association in a population does not identify a mechanism or a threshold.
Individuals with growth hormone receptor deficiency have very low IGF-1 lifelong. The 2011 report found near-absence of cancer and of diabetes in the cohort, and serum from the subjects reduced DNA damage and induced apoptosis in cultured cells. It is a natural experiment on the low end of the axis, consistent with the cohort findings on the high end.
The cohort is small and the finding has been examined but not overturned.
The IGF-1 pathway is a mitogenic and survival signal, and the epidemiology is consistent with that biology. Nothing on this page describes any exposure to the material in this catalogue; it describes what population studies of endogenous IGF-1 found.
IGF-1 LR3 is supplied by REVIVE LAB UAE for laboratory research use only, with identity and purity documented for the batch. It is not for human or veterinary use, and no dosing, administration or protocol guidance is provided.
| Format | Strength | Price | Availability |
|---|---|---|---|
| IGF-1 LR3 Pack | 1 mg | AED 650 | In stock |
Delivery is AED 40 flat and free on orders over AED 700. Payment is cash on delivery anywhere in the UAE, or USDT (TRC20) in advance, which takes 5% off the order total.
Blood was drawn years before diagnosis and IGF-1 measured later in stored samples, so the association is prospective and not caused by the tumour. Many studies since have confirmed modest associations for prostate, breast and colorectal cancer, with relative risks in later meta-analyses lower than the first reports. IGFBP-3 was examined alongside and its role is less consistent.
No. REVIVE LAB UAE supplies research materials and provides no dosing, administration or protocol guidance of any kind. Every product is sold for laboratory research use only and is not for human or veterinary consumption.
Stock is held in Dubai. An order confirmed before 4 PM Dubai time is dispatched the same working day, reaching Dubai and Abu Dhabi the same day and the remaining emirates within 24 hours. Delivery is AED 40 flat and free over AED 700.
Supplied for laboratory research use only. Not for human or veterinary consumption. REVIVE LAB UAE provides no dosing, administration or protocol guidance.