IGF-1 in serum is almost entirely bound to binding proteins, which interfere with antibody binding unless removed by acid-ethanol extraction or blocked by excess IGF-2. Assays differed in how well they did this. They also used in-house calibrators of varying purity and assigned value. Two laboratories could therefore place the same patient inside and outside the normal range.
For a measurement used to diagnose and monitor growth hormone disorders this was a serious limitation.
A recombinant IGF-1 preparation of defined content was adopted as the international standard, so that every manufacturer could calibrate to one material. The consensus recommended mass spectrometry-traceable calibration, complete separation from binding proteins, and population-based reference intervals. Agreement between assays improved substantially in the years after.
Native-sequence recombinant IGF-1, not an analogue, is the standard; IGF-1 LR3 would not be recognised equivalently by the antibodies.
Because IGF-1 measurement is the readout in much of the literature cited across this site, and because the standard illustrates what a reference material does for a protein. The analogue in the pack is not that material.
IGF-1 LR3 is supplied by REVIVE LAB UAE for laboratory research use only, with identity and purity documented for the batch. It is not for human or veterinary use, and no dosing, administration or protocol guidance is provided.
| Format | Strength | Price | Availability |
|---|---|---|---|
| IGF-1 LR3 Pack | 1 mg | AED 650 | In stock |
Delivery is AED 40 flat and free on orders over AED 700. Payment is cash on delivery anywhere in the UAE, or USDT (TRC20) in advance, which takes 5% off the order total.
IGF-1 in serum is almost entirely bound to binding proteins, which interfere with antibody binding unless removed by acid-ethanol extraction or blocked by excess IGF-2. Assays differed in how well they did this. They also used in-house calibrators of varying purity and assigned value. Two laboratories could therefore place the same patient inside and outside the normal range.
No. REVIVE LAB UAE supplies research materials and provides no dosing, administration or protocol guidance of any kind. Every product is sold for laboratory research use only and is not for human or veterinary consumption.
Stock is held in Dubai. An order confirmed before 4 PM Dubai time is dispatched the same working day, reaching Dubai and Abu Dhabi the same day and the remaining emirates within 24 hours. Delivery is AED 40 flat and free over AED 700.
Supplied for laboratory research use only. Not for human or veterinary consumption. REVIVE LAB UAE provides no dosing, administration or protocol guidance.