Western blots and immunofluorescence in cell lines show more MOTS-c after hours of low glucose or after an oxidant challenge, with nuclear accumulation. Muscle biopsies in the 2021 human study show more during exercise. Plasma levels have been reported to change in metabolic disease states in both directions in different cohorts. The cell data are the most consistent.
All depend on antibody detection, with the caveats on the measurement page.
A peptide that rises with energy stress and activates AMPK is behaving like part of the cellular energy-sensing machinery, and one that then enters the nucleus and alters stress-response genes is behaving like a retrograde signal. Both roles are plausible for a mitochondrially encoded molecule and both are proposed in the literature. The regulation is evidence for function in a way that sequence conservation alone is not.
The age-related decline would then represent a weakening of this signal.
Because regulation tells a reader what a molecule is for in a way that effects of administration do not. It describes cell and muscle observations and no use of the pack.
MOTS-c is supplied by REVIVE LAB UAE for laboratory research use only, with identity by mass spectrometry and purity by HPLC for the batch. It is not for human or veterinary use, and no dosing, administration or protocol guidance is provided.
| Format | Strength | Price | Availability |
|---|---|---|---|
| MOTS-c Pack | 40 mg | AED 950 | In stock |
Delivery is AED 40 flat and free on orders over AED 700. Payment is cash on delivery anywhere in the UAE, or USDT (TRC20) in advance, which takes 5% off the order total.
Western blots and immunofluorescence in cell lines show more MOTS-c after hours of low glucose or after an oxidant challenge, with nuclear accumulation. Muscle biopsies in the 2021 human study show more during exercise. Plasma levels have been reported to change in metabolic disease states in both directions in different cohorts. The cell data are the most consistent.
No. REVIVE LAB UAE supplies research materials and provides no dosing, administration or protocol guidance of any kind. Every product is sold for laboratory research use only and is not for human or veterinary consumption.
Stock is held in Dubai. An order confirmed before 4 PM Dubai time is dispatched the same working day, reaching Dubai and Abu Dhabi the same day and the remaining emirates within 24 hours. Delivery is AED 40 flat and free over AED 700.
Supplied for laboratory research use only. Not for human or veterinary consumption. REVIVE LAB UAE provides no dosing, administration or protocol guidance.