The three hormones share enough structural similarity that a single sequence can be tuned toward each receptor. Starting from GIP rather than GLP-1 or glucagon gave high GIP activity by default and allowed the other two to be dialled in by substitution.
This is the same design logic that produced the earlier dual GIP and GLP-1 agonist, and the paper is explicit about the lineage.
Changing residues at positions that contact the receptor alters which receptors the peptide engages and how strongly. Other substitutions improve stability against enzymatic degradation. A modified residue was also introduced as the attachment point for the fatty-acid side chain.
Each change is reported in the paper with its rationale. The result is a peptide whose sequence is related to GIP but is not any natural hormone.
The sequence is the identity. Mass spectrometry confirms a supplied batch against the expected mass, and the expected mass follows from the sequence and its modifications. A supplier who cannot state what the expected mass is cannot have confirmed identity.
The catalogue states a molecular weight for this reason, and lot-specific identity data is available on request.
Retatrutide is supplied by REVIVE LAB UAE as an investigational research material for laboratory use only, with identity by mass spectrometry and purity by HPLC for the batch. It is not approved for any use anywhere, and no dosing, administration or protocol guidance is provided.
| Format | Strength | Price | Availability |
|---|---|---|---|
| Retatrutide Pack | 20 mg | AED 1010 | In stock |
Delivery is AED 40 flat and free on orders over AED 700. Payment is cash on delivery anywhere in the UAE, or USDT (TRC20) in advance, which takes 5% off the order total.
The three hormones share enough structural similarity that a single sequence can be tuned toward each receptor. Starting from GIP rather than GLP-1 or glucagon gave high GIP activity by default and allowed the other two to be dialled in by substitution.
No. REVIVE LAB UAE supplies research materials and provides no dosing, administration or protocol guidance of any kind. Every product is sold for laboratory research use only and is not for human or veterinary consumption.
Stock is held in Dubai. An order confirmed before 4 PM Dubai time is dispatched the same working day, reaching Dubai and Abu Dhabi the same day and the remaining emirates within 24 hours. Delivery is AED 40 flat and free over AED 700.
Supplied for laboratory research use only. Not for human or veterinary consumption. REVIVE LAB UAE provides no dosing, administration or protocol guidance.