Resting heart rate was recorded at scheduled visits as a safety measure. The paper reports the change from baseline by group over time. In the higher dose groups the increase was several beats per minute at its peak and had partly receded by the end of the trial.
This is a vital-sign observation, reported in the safety section with the other measurements.
GLP-1 receptor agonists as a class produce small increases in resting heart rate, documented across their trial programmes and present in their labelling. The mechanism is not fully settled and may involve both direct and reflex effects. Retatrutide engages the GLP-1 receptor and the finding is consistent with the class.
What is not known from phase 2 is whether the glucagon component contributes additionally, since the trials were not designed to separate it.
A heart rate change of this size in a phase 2 trial is a signal to characterise, not a demonstrated harm or a demonstrated absence of one. Large cardiovascular outcome trials are how the class has addressed such signals, and for retatrutide those do not yet exist.
Retatrutide is supplied by REVIVE LAB UAE as an investigational research material for laboratory use only, with identity by mass spectrometry and purity by HPLC for the batch. It is not approved for any use anywhere, and no dosing, administration or protocol guidance is provided.
| Format | Strength | Price | Availability |
|---|---|---|---|
| Retatrutide Pack | 20 mg | AED 1010 | In stock |
Delivery is AED 40 flat and free on orders over AED 700. Payment is cash on delivery anywhere in the UAE, or USDT (TRC20) in advance, which takes 5% off the order total.
Resting heart rate was recorded at scheduled visits as a safety measure. The paper reports the change from baseline by group over time. In the higher dose groups the increase was several beats per minute at its peak and had partly receded by the end of the trial.
No. REVIVE LAB UAE supplies research materials and provides no dosing, administration or protocol guidance of any kind. Every product is sold for laboratory research use only and is not for human or veterinary consumption.
Stock is held in Dubai. An order confirmed before 4 PM Dubai time is dispatched the same working day, reaching Dubai and Abu Dhabi the same day and the remaining emirates within 24 hours. Delivery is AED 40 flat and free over AED 700.
Supplied for laboratory research use only. Not for human or veterinary consumption. REVIVE LAB UAE provides no dosing, administration or protocol guidance.