Two molecules from one sponsor, and no trial that contains both

Published 24 October 2026 · REVIVE LAB UAE Research Desk · 5 min read
Tirzepatide, a GIP and GLP-1 receptor dual agonist, is approved for type 2 diabetes and for weight management and was tested in a phase 3 programme including SURMOUNT-1, published in NEJM in 2022. Retatrutide adds glucagon receptor activity and has published phase 2 trials. No published trial includes both molecules, so any ranking of the two rests on separate trials in different populations.

What tirzepatide has

A completed phase 3 programme and regulatory approval. SURMOUNT-1, reported by Jastreboff and colleagues in NEJM in 2022, randomised 2,539 adults with obesity to placebo or one of three tirzepatide groups for 72 weeks; the highest group recorded a mean weight reduction of 20.9 per cent against 3.1 per cent for placebo. Further phase 3 trials covered type 2 diabetes and other populations.

That is a far larger and longer evidence base than retatrutide currently has.

What retatrutide has

Two published phase 2 trials of 338 and 281 participants over 48 and 36 weeks, a liver-fat substudy, and a phase 3 programme in progress. The obesity trial reported 24.2 per cent in its highest group at 48 weeks. Different trial, different duration, different population, different dose-escalation design.

The number is larger and the trial is smaller and shorter; both facts belong in any comparison.

Why the two cannot be ranked from this

The participants were not randomised between the two molecules. Baseline characteristics, escalation schedules, trial duration and the placebo response all differed. A difference between a 72-week phase 3 figure and a 48-week phase 2 figure is not a measurement of anything.

Retatrutide is supplied by REVIVE LAB UAE as an investigational research material for laboratory use only, with identity by mass spectrometry and purity by HPLC for the batch. It is not approved for any use anywhere, and no dosing, administration or protocol guidance is provided.

What it costs

FormatStrengthPriceAvailability
Retatrutide Pack20 mgAED 1010In stock

Delivery is AED 40 flat and free on orders over AED 700. Payment is cash on delivery anywhere in the UAE, or USDT (TRC20) in advance, which takes 5% off the order total.

Frequently asked

What tirzepatide has?

A completed phase 3 programme and regulatory approval. SURMOUNT-1, reported by Jastreboff and colleagues in NEJM in 2022, randomised 2,539 adults with obesity to placebo or one of three tirzepatide groups for 72 weeks; the highest group recorded a mean weight reduction of 20.9 per cent against 3.1 per cent for placebo. Further phase 3 trials covered type 2 diabetes and other populations.

Does REVIVE LAB UAE provide dosing guidance?

No. REVIVE LAB UAE supplies research materials and provides no dosing, administration or protocol guidance of any kind. Every product is sold for laboratory research use only and is not for human or veterinary consumption.

How fast is delivery in the UAE?

Stock is held in Dubai. An order confirmed before 4 PM Dubai time is dispatched the same working day, reaching Dubai and Abu Dhabi the same day and the remaining emirates within 24 hours. Delivery is AED 40 flat and free over AED 700.

Retatrutide Pack — in stock, dispatched from Dubai
HPLC-verified, lot certificate on every carton, 24-hour delivery nationwide. Browse the catalogue → All peptides UAE

Related reading

Supplied for laboratory research use only. Not for human or veterinary consumption. REVIVE LAB UAE provides no dosing, administration or protocol guidance.