One thymosin beta-4 per actin monomer, with the motif contacting the barbed-end face of actin and the amino-terminal helix lying along it. The complex is in rapid equilibrium, so actin is released as filaments need it. Profilin, the other main monomer-binding protein, competes for the same pool and delivers actin to growing ends, and the balance between the two shapes how fast a cell can rearrange its cytoskeleton.
Nuclear magnetic resonance structures of the complex were reported in the 2000s.
The 1999 wound-healing work on the full protein led to the question of which part was active, and the actin-binding motif was the natural candidate because actin dynamics underlie cell migration. Fragments containing it were tested and reported to retain migration-promoting activity in culture. Whether a fragment reproduces the extracellular effects of the full protein in vivo is inferred rather than established, as the mass page states.
The fragment in this catalogue is defined by containing this region.
Because the motif is the molecular reason the fragment exists and the thing a certificate identifies. It describes biochemistry and no use of the pack.
The BPC-157 + TB500 blend is supplied by REVIVE LAB UAE for laboratory research use only, with identity by mass spectrometry and purity by HPLC for each component of the batch. It is not for human or veterinary use, and no dosing, administration or protocol guidance is provided.
| Format | Strength | Price | Availability |
|---|---|---|---|
| BPC-157 + TB500 Pack | 5 mg + 5 mg | AED 510 | In stock |
Delivery is AED 40 flat and free on orders over AED 700. Payment is cash on delivery anywhere in the UAE, or USDT (TRC20) in advance, which takes 5% off the order total.
One thymosin beta-4 per actin monomer, with the motif contacting the barbed-end face of actin and the amino-terminal helix lying along it. The complex is in rapid equilibrium, so actin is released as filaments need it. Profilin, the other main monomer-binding protein, competes for the same pool and delivers actin to growing ends, and the balance between the two shapes how fast a cell can rearrange its cytoskeleton.
No. REVIVE LAB UAE supplies research materials and provides no dosing, administration or protocol guidance of any kind. Every product is sold for laboratory research use only and is not for human or veterinary consumption.
Stock is held in Dubai. An order confirmed before 4 PM Dubai time is dispatched the same working day, reaching Dubai and Abu Dhabi the same day and the remaining emirates within 24 hours. Delivery is AED 40 flat and free over AED 700.
Supplied for laboratory research use only. Not for human or veterinary consumption. REVIVE LAB UAE provides no dosing, administration or protocol guidance.