Clusters of deaths in neonatal intensive care with a distinctive picture: acidosis, gasping, neurological deterioration, and high levels of benzyl alcohol and its metabolite benzoic acid in blood and urine. The common factor was repeated flushing of catheters with preserved solutions, so that infants weighing around a kilogram received grams of the preservative over days.
Once the flushes were changed to unpreserved solutions the syndrome stopped.
Benzyl alcohol is oxidised to benzoic acid and then conjugated with glycine to hippuric acid for excretion. Premature infants have little capacity for the conjugation step, so benzoic acid accumulated and drove the acidosis. In older children and adults the pathway handles the amounts present in a preserved product without difficulty. The toxicity was a matter of immature metabolism and extreme cumulative exposure.
This is why the warning is specific to newborns rather than general.
The pharmacopoeial monograph requires the statement, and it is printed on the vials in this pack as on all such vials. It is a historical safety requirement, reported here as history, and not a description of any use of the product.
Bacteriostatic water is supplied by REVIVE LAB UAE as a diluent for lyophilised research peptides, for laboratory research use only. It is not for human or veterinary use, and no dosing, administration or protocol guidance is provided.
| Format | Strength | Price | Availability |
|---|---|---|---|
| Bacteriostatic Water | 3 mL × 2 | AED 99 | In stock |
Delivery is AED 40 flat and free on orders over AED 700. Payment is cash on delivery anywhere in the UAE, or USDT (TRC20) in advance, which takes 5% off the order total.
Clusters of deaths in neonatal intensive care with a distinctive picture: acidosis, gasping, neurological deterioration, and high levels of benzyl alcohol and its metabolite benzoic acid in blood and urine. The common factor was repeated flushing of catheters with preserved solutions, so that infants weighing around a kilogram received grams of the preservative over days.
No. REVIVE LAB UAE supplies research materials and provides no dosing, administration or protocol guidance of any kind. Every product is sold for laboratory research use only and is not for human or veterinary consumption.
Stock is held in Dubai. An order confirmed before 4 PM Dubai time is dispatched the same working day, reaching Dubai and Abu Dhabi the same day and the remaining emirates within 24 hours. Delivery is AED 40 flat and free over AED 700.
Supplied for laboratory research use only. Not for human or veterinary consumption. REVIVE LAB UAE provides no dosing, administration or protocol guidance.