Lysyl oxidase and its four relatives act outside the cell on assembled collagen fibrils and elastin. The aldehyde products react with neighbouring lysines and with each other to form the pyridinoline and desmosine cross-links that mature matrix contains. Cross-linking increases with age and is part of why old collagen is stiff and resistant to turnover. The enzyme is also implicated in fibrosis and in tumour matrix stiffening.
It is one of about a dozen copper enzymes in humans, alongside ceruloplasmin, cytochrome c oxidase and superoxide dismutase.
The enzyme acquires copper inside the cell before secretion, through the transporter ATP7A in the secretory pathway. Cells therefore need an adequate copper supply to make active enzyme, and copper-deficient fibroblasts secrete inactive protein. A copper complex that cells take up would feed this pathway. Whether GHK-Cu does so in any tissue, and whether that matters beside dietary copper, is not established; the pathway is.
This is one of the routes the copper-delivery hypothesis proposes.
Because the biology of copper in connective tissue is the reason a copper peptide was thought worth studying in that tissue. It describes biochemistry and no use of the pack.
GHK-Cu is supplied by REVIVE LAB UAE for laboratory research use only, with identity by mass spectrometry and purity by HPLC for the batch. It is not for human or veterinary use, and no dosing, administration or protocol guidance is provided.
| Format | Strength | Price | Availability |
|---|---|---|---|
| GHK-Cu Pack | 50 mg | AED 425 | In stock |
Delivery is AED 40 flat and free on orders over AED 700. Payment is cash on delivery anywhere in the UAE, or USDT (TRC20) in advance, which takes 5% off the order total.
Lysyl oxidase and its four relatives act outside the cell on assembled collagen fibrils and elastin. The aldehyde products react with neighbouring lysines and with each other to form the pyridinoline and desmosine cross-links that mature matrix contains. Cross-linking increases with age and is part of why old collagen is stiff and resistant to turnover. The enzyme is also implicated in fibrosis and in tumour matrix stiffening.
No. REVIVE LAB UAE supplies research materials and provides no dosing, administration or protocol guidance of any kind. Every product is sold for laboratory research use only and is not for human or veterinary consumption.
Stock is held in Dubai. An order confirmed before 4 PM Dubai time is dispatched the same working day, reaching Dubai and Abu Dhabi the same day and the remaining emirates within 24 hours. Delivery is AED 40 flat and free over AED 700.
Supplied for laboratory research use only. Not for human or veterinary consumption. REVIVE LAB UAE provides no dosing, administration or protocol guidance.