Four long helices pack against one another with two long crossover connections, giving the up-up-down-down arrangement characteristic of the class I helical cytokines. The chain is held by two disulfide bonds. The molecule is compact, globular and about 22 kilodaltons.
This is a protein fold, not a peptide conformation: it has a hydrophobic core and a defined tertiary structure that can be lost.
The 1992 Science paper from Genentech reported the crystal structure of growth hormone in complex with the extracellular domain of its receptor at 2.8 angstrom resolution. It showed one hormone molecule contacting two receptor molecules, a result that reorganised how receptor activation in this family was understood.
Earlier work had established the sequence and the disulfide pattern; the crystal structure fixed the three-dimensional picture.
Prolactin, placental lactogen, erythropoietin and a number of interleukins share the fold and the general mode of receptor binding. Growth hormone became the model system for the whole class because its structure came first and its receptor interactions were mapped residue by residue.
Somatropin is supplied by REVIVE LAB UAE for laboratory research use only, with identity and purity documented for the batch. It is not for human or veterinary use, and no dosing, administration or protocol guidance is provided.
| Format | Strength | Price | Availability |
|---|---|---|---|
| HGH Somatropin Pack | 24 mg (72 IU) | AED 850 | In stock |
Delivery is AED 40 flat and free on orders over AED 700. Payment is cash on delivery anywhere in the UAE, or USDT (TRC20) in advance, which takes 5% off the order total.
Four long helices pack against one another with two long crossover connections, giving the up-up-down-down arrangement characteristic of the class I helical cytokines. The chain is held by two disulfide bonds. The molecule is compact, globular and about 22 kilodaltons.
No. REVIVE LAB UAE supplies research materials and provides no dosing, administration or protocol guidance of any kind. Every product is sold for laboratory research use only and is not for human or veterinary consumption.
Stock is held in Dubai. An order confirmed before 4 PM Dubai time is dispatched the same working day, reaching Dubai and Abu Dhabi the same day and the remaining emirates within 24 hours. Delivery is AED 40 flat and free over AED 700.
Supplied for laboratory research use only. Not for human or veterinary consumption. REVIVE LAB UAE provides no dosing, administration or protocol guidance.