Proportionate dwarfism, delayed puberty, increased adiposity with paradoxically improved insulin sensitivity, low cancer incidence, and extended lifespan in both sexes. Metabolic rate is altered and the mice resist diet-induced diabetes. The picture matches the Ecuadorian Laron cohort in its outlines — short, insulin-sensitive, cancer-resistant — which is one reason the human and mouse data reinforce each other.
They were awarded a prize for mouse longevity in 2003.
Giving IGF-1 to these mice, or crossing them with mice overexpressing it, partly restores growth and some organ sizes but not others, and it does not restore the direct metabolic actions of growth hormone — lipolysis, insulin antagonism — because those need the receptor the mice lack. The experiment is the in vivo complement of the dual effector theory: IGF-1 accounts for part of what growth hormone does, and growth hormone does the rest itself.
Whether restoring IGF-1 shortens their lifespan has been studied with mixed results.
Because it is the cleanest living system for separating IGF-1 action from growth hormone action, and both hormones are in this catalogue. It describes mouse genetics and no use of the pack.
IGF-1 LR3 is supplied by REVIVE LAB UAE for laboratory research use only, with identity and purity documented for the batch. It is not for human or veterinary use, and no dosing, administration or protocol guidance is provided.
| Format | Strength | Price | Availability |
|---|---|---|---|
| IGF-1 LR3 Pack | 1 mg | AED 650 | In stock |
Delivery is AED 40 flat and free on orders over AED 700. Payment is cash on delivery anywhere in the UAE, or USDT (TRC20) in advance, which takes 5% off the order total.
Proportionate dwarfism, delayed puberty, increased adiposity with paradoxically improved insulin sensitivity, low cancer incidence, and extended lifespan in both sexes. Metabolic rate is altered and the mice resist diet-induced diabetes. The picture matches the Ecuadorian Laron cohort in its outlines — short, insulin-sensitive, cancer-resistant — which is one reason the human and mouse data reinforce each other.
No. REVIVE LAB UAE supplies research materials and provides no dosing, administration or protocol guidance of any kind. Every product is sold for laboratory research use only and is not for human or veterinary consumption.
Stock is held in Dubai. An order confirmed before 4 PM Dubai time is dispatched the same working day, reaching Dubai and Abu Dhabi the same day and the remaining emirates within 24 hours. Delivery is AED 40 flat and free over AED 700.
Supplied for laboratory research use only. Not for human or veterinary consumption. REVIVE LAB UAE provides no dosing, administration or protocol guidance.