Rats made catabolic by dexamethasone, by surgical removal of part of the small intestine, or by other insults, in which native IGF-1 had shown modest anabolic effects. The analogue was compared with native IGF-1 and with vehicle over periods of days to weeks, with weight, organ mass and nitrogen balance as endpoints.
Animal numbers were small by later standards and the work was published across several papers in endocrinology journals.
Native IGF-1 enters the ternary complex and acquires a half-life of hours; the analogue, excluded from it, has a half-life of minutes. Plasma levels of the analogue were therefore lower and briefer. The group interpreted the greater effect as the free analogue reaching tissue receptors that complexed native IGF-1 could not.
The same work noted that the analogue lowered blood glucose more than native IGF-1 at equal amounts, for the same reason.
Preclinical pharmacology from the developers of the molecule, three decades old, in rats. It established the properties that made the analogue a culture reagent. It is not evidence about any other setting, and this page describes it as history.
IGF-1 LR3 is supplied by REVIVE LAB UAE for laboratory research use only, with identity and purity documented for the batch. It is not for human or veterinary use, and no dosing, administration or protocol guidance is provided.
| Format | Strength | Price | Availability |
|---|---|---|---|
| IGF-1 LR3 Pack | 1 mg | AED 650 | In stock |
Delivery is AED 40 flat and free on orders over AED 700. Payment is cash on delivery anywhere in the UAE, or USDT (TRC20) in advance, which takes 5% off the order total.
Rats made catabolic by dexamethasone, by surgical removal of part of the small intestine, or by other insults, in which native IGF-1 had shown modest anabolic effects. The analogue was compared with native IGF-1 and with vehicle over periods of days to weeks, with weight, organ mass and nitrogen balance as endpoints.
No. REVIVE LAB UAE supplies research materials and provides no dosing, administration or protocol guidance of any kind. Every product is sold for laboratory research use only and is not for human or veterinary consumption.
Stock is held in Dubai. An order confirmed before 4 PM Dubai time is dispatched the same working day, reaching Dubai and Abu Dhabi the same day and the remaining emirates within 24 hours. Delivery is AED 40 flat and free over AED 700.
Supplied for laboratory research use only. Not for human or veterinary consumption. REVIVE LAB UAE provides no dosing, administration or protocol guidance.