Cultured cells secrete IGF-binding proteins. Native IGF-1 added to the medium is captured by them and must be added in excess. Insulin, which the binding proteins do not bind, was used instead, but it acts on the IGF-1 receptor only weakly and needs very high concentration. LR3 acts on the receptor at native affinity and escapes the binding proteins, so a small amount suffices.
The media-supplement literature reports activity at nanogram-per-millilitre concentrations.
In defined and chemically defined media for antibody and recombinant protein production, in some stem cell and primary culture media, and in research culture where a defined IGF-1 receptor agonist is wanted without serum. Commercial preparations for this purpose are made recombinantly to animal-origin-free standards.
This industrial use is by far the largest use of the molecule.
IGF-1 LR3 is, in origin and in its main market, a cell culture reagent. The pack in this catalogue is that reagent supplied in a 1 mg vial for laboratory research. Nothing on this page describes any other use.
IGF-1 LR3 is supplied by REVIVE LAB UAE for laboratory research use only, with identity and purity documented for the batch. It is not for human or veterinary use, and no dosing, administration or protocol guidance is provided.
| Format | Strength | Price | Availability |
|---|---|---|---|
| IGF-1 LR3 Pack | 1 mg | AED 650 | In stock |
Delivery is AED 40 flat and free on orders over AED 700. Payment is cash on delivery anywhere in the UAE, or USDT (TRC20) in advance, which takes 5% off the order total.
Cultured cells secrete IGF-binding proteins. Native IGF-1 added to the medium is captured by them and must be added in excess. Insulin, which the binding proteins do not bind, was used instead, but it acts on the IGF-1 receptor only weakly and needs very high concentration. LR3 acts on the receptor at native affinity and escapes the binding proteins, so a small amount suffices.
No. REVIVE LAB UAE supplies research materials and provides no dosing, administration or protocol guidance of any kind. Every product is sold for laboratory research use only and is not for human or veterinary consumption.
Stock is held in Dubai. An order confirmed before 4 PM Dubai time is dispatched the same working day, reaching Dubai and Abu Dhabi the same day and the remaining emirates within 24 hours. Delivery is AED 40 flat and free over AED 700.
Supplied for laboratory research use only. Not for human or veterinary consumption. REVIVE LAB UAE provides no dosing, administration or protocol guidance.