Binding proteins are produced by the cells themselves, so the amount present rises as the culture grows and differs between cell types. Added IGF-1 partitions between bound and free, and only the free fraction engages receptors.
None of that is visible from the pipette. A plate seeded at two densities can present two different effective exposures from the same nominal addition.
A curve plots response against what was added. If what was available is a shifting fraction of that, the curve is distorted in a way that is not random — it varies systematically with conditions that also change over the course of an experiment.
A curve of that kind compared between laboratories, or between time points, compares quantities that were never the same measurement.
Measurement of the free fraction, or substitution of an analogue with reduced binding-protein affinity — which is the reason LR3 was developed and the reason it is common in culture work. The second substitutes a different material for a measurement problem, and where binding-protein interaction is itself under study it removes the object of study.
IGF-1 LR3 is supplied here with lot-specific documentation, for laboratory research use only.
| Format | Strength | Price | Availability |
|---|---|---|---|
| IGF-1 LR3 Pack | 1 mg | AED 650 | In stock |
Delivery is AED 40 flat and free on orders over AED 700. Payment is cash on delivery anywhere in the UAE, or USDT (TRC20) in advance, which takes 5% off the order total.
Binding proteins are produced by the cells themselves, so the amount present rises as the culture grows and differs between cell types. Added IGF-1 partitions between bound and free, and only the free fraction engages receptors.
No. REVIVE LAB UAE supplies research materials and provides no dosing, administration or protocol guidance of any kind. Every product is sold for laboratory research use only and is not for human or veterinary consumption.
Stock is held in Dubai. An order confirmed before 4 PM Dubai time is dispatched the same working day, reaching Dubai and Abu Dhabi the same day and the remaining emirates within 24 hours. Delivery is AED 40 flat and free over AED 700.
Supplied for laboratory research use only. Not for human or veterinary consumption. REVIVE LAB UAE provides no dosing, administration or protocol guidance.