Young and old mice were compared for MOTS-c content in muscle by western blot and in plasma by enzyme-linked immunoassay; both were lower in old animals. The finding was part of the case for the peptide as a metabolic regulator whose loss accompanies ageing, parallel to earlier reports of humanin declining with age.
It is an association in a cross-sectional comparison, not a demonstration of cause.
Several groups have measured plasma MOTS-c in cohorts of different ages and in disease states, generally reporting lower levels with age and in some metabolic conditions. The exercise study of 2021 found levels rising in muscle and plasma after a bout of exercise in young men. Sample sizes are small and methods differ.
No study has measured levels across the lifespan in one population with one method.
A 16-residue peptide at low concentration in plasma is hard to measure specifically; antibodies can cross-react with fragments or precursors, and oxidised forms may or may not be detected. Mass spectrometric methods are emerging. The direction of the age effect is reasonably consistent; the magnitude is not established.
MOTS-c is supplied by REVIVE LAB UAE for laboratory research use only, with identity by mass spectrometry and purity by HPLC for the batch. It is not for human or veterinary use, and no dosing, administration or protocol guidance is provided.
| Format | Strength | Price | Availability |
|---|---|---|---|
| MOTS-c Pack | 40 mg | AED 950 | In stock |
Delivery is AED 40 flat and free on orders over AED 700. Payment is cash on delivery anywhere in the UAE, or USDT (TRC20) in advance, which takes 5% off the order total.
Young and old mice were compared for MOTS-c content in muscle by western blot and in plasma by enzyme-linked immunoassay; both were lower in old animals. The finding was part of the case for the peptide as a metabolic regulator whose loss accompanies ageing, parallel to earlier reports of humanin declining with age.
No. REVIVE LAB UAE supplies research materials and provides no dosing, administration or protocol guidance of any kind. Every product is sold for laboratory research use only and is not for human or veterinary consumption.
Stock is held in Dubai. An order confirmed before 4 PM Dubai time is dispatched the same working day, reaching Dubai and Abu Dhabi the same day and the remaining emirates within 24 hours. Delivery is AED 40 flat and free over AED 700.
Supplied for laboratory research use only. Not for human or veterinary consumption. REVIVE LAB UAE provides no dosing, administration or protocol guidance.