Both come from the same 108-residue precursor. Cleavage after residue 44 with amidation gives the major form; cleavage at an internal basic site gives the 40-residue acid. Their relative proportions vary by tissue. Both bind the receptor with similar affinity and release growth hormone with similar potency, and both are inactivated by the same amino-terminal cleavage.
A still shorter natural fragment, 1-29, is the sermorelin sequence and retains full activity.
The carboxyl-terminal residues add helix-stabilising contacts with the receptor extracellular domain and slow degradation from the carboxyl end. For a drug, the longer backbone gave the best affinity and stability the natural sequence offered, and the single amino-terminal modification addressed the one weakness all forms share. Shortening the backbone, as sermorelin did, saved synthesis cost at the expense of affinity.
The 44-residue amide is therefore the natural hormone at its most stable, plus one acyl group.
Because the two natural forms are part of the record of the hormone and explain a design choice. It describes biochemistry and no use of the pack.
Tesamorelin is supplied by REVIVE LAB UAE for laboratory research use only, with identity by mass spectrometry and purity by HPLC for the batch. It is not for human or veterinary use, and no dosing, administration or protocol guidance is provided.
| Format | Strength | Price | Availability |
|---|---|---|---|
| Tesamorelin Pack | 20 mg | AED 1010 | In stock |
Delivery is AED 40 flat and free on orders over AED 700. Payment is cash on delivery anywhere in the UAE, or USDT (TRC20) in advance, which takes 5% off the order total.
Both come from the same 108-residue precursor. Cleavage after residue 44 with amidation gives the major form; cleavage at an internal basic site gives the 40-residue acid. Their relative proportions vary by tissue. Both bind the receptor with similar affinity and release growth hormone with similar potency, and both are inactivated by the same amino-terminal cleavage.
No. REVIVE LAB UAE supplies research materials and provides no dosing, administration or protocol guidance of any kind. Every product is sold for laboratory research use only and is not for human or veterinary consumption.
Stock is held in Dubai. An order confirmed before 4 PM Dubai time is dispatched the same working day, reaching Dubai and Abu Dhabi the same day and the remaining emirates within 24 hours. Delivery is AED 40 flat and free over AED 700.
Supplied for laboratory research use only. Not for human or veterinary consumption. REVIVE LAB UAE provides no dosing, administration or protocol guidance.