Re-randomisation after the primary endpoint is the standard way to test durability. Participants and investigators remained blinded. Visceral fat was measured by computed tomography at a single abdominal level at baseline, 26 and 52 weeks. The regain curve in the switch group mirrored the loss curve in the first phase.
IGF-1 also returned to baseline in the switch group, confirming the pharmacological withdrawal.
The drug changes the growth hormone environment and the fat responds; remove the drug and the environment reverts. There is no remodelling that persists. This places tesamorelin among treatments that manage a state rather than correct it, which is also true of most metabolic drugs. For a regulator it meant the label must say so; for the field it meant that any benefit depends on continued exposure, with the costs and risks that entails.
The parallel with the weight regain after stopping semaglutide, documented in the STEP extension trials, is close.
Because the durability question is one a reader of any body-composition trial should ask, and for tesamorelin it was asked and answered. It describes a trial finding and no use of the pack.
Tesamorelin is supplied by REVIVE LAB UAE for laboratory research use only, with identity by mass spectrometry and purity by HPLC for the batch. It is not for human or veterinary use, and no dosing, administration or protocol guidance is provided.
| Format | Strength | Price | Availability |
|---|---|---|---|
| Tesamorelin Pack | 20 mg | AED 1010 | In stock |
Delivery is AED 40 flat and free on orders over AED 700. Payment is cash on delivery anywhere in the UAE, or USDT (TRC20) in advance, which takes 5% off the order total.
Re-randomisation after the primary endpoint is the standard way to test durability. Participants and investigators remained blinded. Visceral fat was measured by computed tomography at a single abdominal level at baseline, 26 and 52 weeks. The regain curve in the switch group mirrored the loss curve in the first phase.
No. REVIVE LAB UAE supplies research materials and provides no dosing, administration or protocol guidance of any kind. Every product is sold for laboratory research use only and is not for human or veterinary consumption.
Stock is held in Dubai. An order confirmed before 4 PM Dubai time is dispatched the same working day, reaching Dubai and Abu Dhabi the same day and the remaining emirates within 24 hours. Delivery is AED 40 flat and free over AED 700.
Supplied for laboratory research use only. Not for human or veterinary consumption. REVIVE LAB UAE provides no dosing, administration or protocol guidance.