Sixteen amino acids, and what each group of them contributes to the molecule

Published 26 October 2026 · REVIVE LAB UAE Research Desk · 5 min read
The 16-residue sequence of MOTS-c is MRWQEMGYIFYPRKLR. It begins and has a sixth residue of methionine, both oxidisable. It carries one tryptophan and two tyrosines, which absorb ultraviolet light at 280 nanometres and make the peptide quantifiable by absorbance. Four basic residues — three arginines and a lysine — against two glutamates give a net positive charge. Isoleucine, phenylalanine, leucine and the aromatics make it more hydrophobic than most short peptides in the catalogue.

The oxidisable residues

Methionine at positions 1 and 6 can each oxidise to the sulfoxide, adding sixteen daltons; tryptophan at position 3 is sensitive to light and oxidants. Three of sixteen residues are therefore oxidation targets, a high proportion, and the degradation chemistry of the peptide is dominated by them.

A certificate for the peptide reports oxidised forms within related substances.

The aromatic residues

Tryptophan and two tyrosines give the peptide a molar absorptivity near 280 nanometres of roughly 8,500 per molar per centimetre, enough to measure concentration directly by spectrophotometer. GHK-Cu and BPC-157 lack this; among the short peptides in the catalogue, MOTS-c is unusual in being readable at 280.

The same residues contribute to its hydrophobicity and its retention on reversed-phase columns.

Charge and the rest

Arginines at 2, 13 and 16 and lysine at 14 are positive; glutamates at 5 and 6 — the fifth residue and the one after the second methionine is glycine — glutamate at 5 is the acidic residue, together with the carboxyl terminus. The net charge is positive at neutral pH. Proline at 12 introduces a kink; glycine at 7 adds flexibility. The peptide is unstructured in water and may adopt structure on membranes.

MOTS-c is supplied by REVIVE LAB UAE for laboratory research use only, with identity by mass spectrometry and purity by HPLC for the batch. It is not for human or veterinary use, and no dosing, administration or protocol guidance is provided.

What it costs

FormatStrengthPriceAvailability
MOTS-c Pack40 mgAED 950In stock

Delivery is AED 40 flat and free on orders over AED 700. Payment is cash on delivery anywhere in the UAE, or USDT (TRC20) in advance, which takes 5% off the order total.

Frequently asked

The oxidisable residues?

Methionine at positions 1 and 6 can each oxidise to the sulfoxide, adding sixteen daltons; tryptophan at position 3 is sensitive to light and oxidants. Three of sixteen residues are therefore oxidation targets, a high proportion, and the degradation chemistry of the peptide is dominated by them.

Does REVIVE LAB UAE provide dosing guidance?

No. REVIVE LAB UAE supplies research materials and provides no dosing, administration or protocol guidance of any kind. Every product is sold for laboratory research use only and is not for human or veterinary consumption.

How fast is delivery in the UAE?

Stock is held in Dubai. An order confirmed before 4 PM Dubai time is dispatched the same working day, reaching Dubai and Abu Dhabi the same day and the remaining emirates within 24 hours. Delivery is AED 40 flat and free over AED 700.

MOTS-c Pack — in stock, dispatched from Dubai
HPLC-verified, lot certificate on every carton, 24-hour delivery nationwide. Browse the catalogue → All peptides UAE

Related reading

Supplied for laboratory research use only. Not for human or veterinary consumption. REVIVE LAB UAE provides no dosing, administration or protocol guidance.