The thioether side chain is the most readily oxidised group in a peptide. The sulfoxide is more polar, so oxidised forms elute earlier on reversed phase and are resolved from the parent. The amino-terminal methionine is fully exposed; position 6 is in the middle of a short unstructured chain and equally accessible. Both oxidise at similar rates.
Oxidation is reversible in cells by methionine sulfoxide reductases, but not in a vial.
The indole ring absorbs ultraviolet light and can be excited to react with oxygen, giving a range of products. The reaction needs light, which is why the storage line specifies protection from it. Tryptophan oxidation also quenches the fluorescence the residue otherwise provides.
Three of sixteen residues oxidisable is a high fraction compared with most peptides in the catalogue.
Reversed-phase chromatography resolves the oxidised forms; mass spectrometry confirms them by the added mass. A certificate reports them within related substances. A lot with low oxidised content and sealed under its printed conditions stays that way; an opened vial does not.
MOTS-c is supplied by REVIVE LAB UAE for laboratory research use only, with identity by mass spectrometry and purity by HPLC for the batch. It is not for human or veterinary use, and no dosing, administration or protocol guidance is provided.
| Format | Strength | Price | Availability |
|---|---|---|---|
| MOTS-c Pack | 40 mg | AED 950 | In stock |
Delivery is AED 40 flat and free on orders over AED 700. Payment is cash on delivery anywhere in the UAE, or USDT (TRC20) in advance, which takes 5% off the order total.
The thioether side chain is the most readily oxidised group in a peptide. The sulfoxide is more polar, so oxidised forms elute earlier on reversed phase and are resolved from the parent. The amino-terminal methionine is fully exposed; position 6 is in the middle of a short unstructured chain and equally accessible. Both oxidise at similar rates.
No. REVIVE LAB UAE supplies research materials and provides no dosing, administration or protocol guidance of any kind. Every product is sold for laboratory research use only and is not for human or veterinary consumption.
Stock is held in Dubai. An order confirmed before 4 PM Dubai time is dispatched the same working day, reaching Dubai and Abu Dhabi the same day and the remaining emirates within 24 hours. Delivery is AED 40 flat and free over AED 700.
Supplied for laboratory research use only. Not for human or veterinary consumption. REVIVE LAB UAE provides no dosing, administration or protocol guidance.