Most compounds in a peptide catalogue act on a receptor. Follistatin does not: it binds its targets directly and holds them, so they cannot reach the receptors they would otherwise activate. The effect is subtraction rather than addition.
Nakamura and colleagues reported in 1990 that follistatin binds activin, which established the mechanism. Everything written about follistatin since rests on that: it is a sink for particular proteins.
Activins, and other members of the transforming growth factor beta superfamily, with different affinities. The family is large and the binding is not uniform across it, which is why "follistatin blocks TGF-beta" is too loose a statement to be useful.
Which targets matter depends entirely on the system being studied, because what is present to be bound differs between tissues and between culture conditions.
An antagonist that works by sequestration produces an effect proportional to how much of its target is around. In a system where the target is scarce, adding follistatin may do very little, and that is a property of the model rather than a failure of the material.
The composition of the system therefore bounds what the addition can produce in it. REVIVE LAB UAE offers no dosing or protocol guidance of any kind.
The carton and vial are labelled Follistatin-344, with a lot-specific Certificate of Analysis stating the measured purity for that batch.
Research use only, not for human or veterinary consumption.
| Format | Strength | Price | Availability |
|---|---|---|---|
| Follistatin-344 Pack | 1 mg | AED 750 | In stock |
Delivery is AED 40 flat and free on orders over AED 700. Payment is cash on delivery anywhere in the UAE, or USDT (TRC20) in advance, which takes 5% off the order total.
Most compounds in a peptide catalogue act on a receptor. Follistatin does not: it binds its targets directly and holds them, so they cannot reach the receptors they would otherwise activate. The effect is subtraction rather than addition.
No. REVIVE LAB UAE supplies research materials and provides no dosing, administration or protocol guidance of any kind. Every product is sold for laboratory research use only and is not for human or veterinary consumption.
Stock is held in Dubai. An order confirmed before 4 PM Dubai time is dispatched the same working day, reaching Dubai and Abu Dhabi the same day and the remaining emirates within 24 hours. Delivery is AED 40 flat and free over AED 700.
Supplied for laboratory research use only. Not for human or veterinary consumption. REVIVE LAB UAE provides no dosing, administration or protocol guidance.